Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics.
Erythromycin will not treat a viral infection such as the common cold or flu. This medicine can cause unusual results with certain lab tests of the urine. Tell any doctor who treats you that you are using erythromycin. Store at room temperature away from moisture, heat, and light.
You may need to store liquid medicine in a refrigerator. Carefully follow the storage directions on your medicine label. Liquid medicine expires after a short period of time. Throw away any unused liquid as directed. Dosage Information in more detail What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at What should I avoid while taking erythromycin? Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking erythromycin and call your doctor.
Do not use anti-diarrhea medicine unless your doctor tells you to. Erythromycin side effects Get emergency medical help if you have any of these signs of an allergic reaction to erythromycin: Call your doctor at once if you have: Older adults may be more likely to have serious side effects from erythromycin, including hearing loss, or a life-threatening fast heart rate.
Common erythromycin side effects may include: This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Mild to moderate infection: Usual Adult Dose of Erythromycin for Chancroid: Usual Adult Dose for Lymphogranuloma Venereum: Usual Adult Dose for Mycoplasma Pneumonia: Usual Adult Dose for Otitis Media: Usual Adult Dose for Pharyngitis: Erythromycin is an inhibitor of the cytochrome P system, which means it can have a rapid effect on levels of other drugs metabolised by this system, e.
If other CYP3A substrates — drugs that are broken down by CYP3A — such as simvastatin Zocor , lovastatin Mevacor , or atorvastatin Lipitor —are taken concomitantly with erythromycin, levels of the substrates increase, often causing adverse effects. A noted drug interaction involves erythromycin and simvastatin, resulting in increased simvastatin levels and the potential for rhabdomyolysis.
Another group of CYP3A4 substrates are drugs used for migraine such as ergotamine and dihydroergotamine ; their adverse effects may be more pronounced if erythromycin is associated. Other examples include terfenadine Seldane, Seldane-D , astemizole Hismanal , cisapride Propulsid, withdrawn in many countries for prolonging the QT time and pimozide Orap. Theophylline , which is used mostly in asthma, is also contraindicated.
Erythromycin and doxycycline can have a synergistic effect when combined and kill bacteria E. This synergistic relationship is only temporary. By binding to the 50s subunit of the bacterial rRNA complex, protein synthesis and subsequent structure and function processes critical for life or replication are inhibited. Without this translocation, the A site remains occupied, thus the addition of an incoming tRNA and its attached amino acid to the nascent polypeptide chain is inhibited.
This interferes with the production of functionally useful proteins, which is the basis of this antimicrobial action. Erythromycin increases gut motility by binding to Motillin, thus it is a Motillin receptor agonist in addition to its antimicrobial properties. Pharmacokinetics[ edit ] Erythromycin is easily inactivated by gastric acid; therefore, all orally administered formulations are given as either enteric-coated or more-stable salts or esters , such as erythromycin ethylsuccinate.
Erythromycin is very rapidly absorbed, and diffuses into most tissues and phagocytes. Due to the high concentration in phagocytes, erythromycin is actively transported to the site of infection, where, during active phagocytosis , large concentrations of erythromycin are released.
If a child is using this medicine, tell your doctor if the child has any changes in weight. This is not a complete list of side effects and erythromycin may occur. This medicine can cause unusual results with certain lab tests of the urine. If other CYP3A substrates — drugs that are broken down by CYP3A — such as simvastatin Zocorlovastatin Mevacoror atorvastatin Lipitor —are taken concomitantly with erythromycin, levels of the substrates increase, often causing adverse effects. Usual Adult Dose for Pneumonia: Other examples include terfenadine Seldane, Seldane-Derythromycin a price, astemizole Hismanalcisapride Propulsid, withdrawn in many prices for prolonging the QT time and pimozide Orap. Erythromycin and doxycycline can have a synergistic effect when combined and kill bacteria E. Erythromycin's elimination half-life ranges between 1. If you do not have a dose-measuring device, ask your pharmacist for one. Erythromycin can pass into breast milk and may harm sildenafil teva 100mg tablets nursing baby. Do not take this medicine in larger or smaller amounts or for longer than recommended.
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