Tell your doctor if you are taking medications, such as alpha-blockers e. Sildenafil does not protect against sexually transmitted infections such as HIV. If you experience a sudden loss of vision in one or both eyes or other vision related problems, contact your doctor immediately. Vision loss may be partial or complete. While in some cases the condition may improve over time, it can also be permanent.
This rare condition is more likely to occur if you have heart disease, high blood pressure, high cholesterol, diabetes, or eye problems, are more than 50 years old, or if you smoke. If you have any eye conditions, such as retinitis pigmentosa or non-arteritic anterior ischemic optic neuropathy NAION , tell your doctor. Sildenafil is not intended for use by women. Sildenafil is not intended for use by children or adolescents under 18 years of age. What do you have to consider before using it?
Do not take Sildenafil Teva If you are taking medicines containing nitrates, as the combination may cause a potentially dangerous decrease in your blood pressure. Tell your doctor if you are taking any of these medicines which are often given for relief of angina pectoris?
If you are not certain, ask your doctor or pharmacist. If you are using any of the drugs known as nitric oxide donors such as amyl nitrite? If you are allergic hypersensitive to sildenafil or any of the other ingredients of Sildenafil Teva. If you have a severe heart or liver problem. If you have recently had a stroke or a heart attack, or if you have low blood pressure. If you have certain rare inherited eye diseases such as retinitis pigmentosa.
If you have ever had loss of vision because of non-arteritic anterior ischaemic optic neuropathy NAION. Take special care with Sildenafil Teva Tell your doctor If you have sickle cell anaemia an abnormality of red blood cells , leukaemia cancer of blood cells , multiple myeloma cancer of bone marrow or If you have a deformity of your penis or Peyronie? If you have problems with your heart.
Your doctor should in that case carefully check whether your heart can take the additional strain of having sex. If you currently have a stomach ulcer, or a bleeding disorder such as haemophilia. If you experience sudden decrease or loss of vision, stop taking Sildenafil Teva and contact your doctor immediately. You should not use Sildenafil Teva with any other treatment for erectile dysfunction.
An allergic reaction this occurs uncommonly may affect up to 1 in people. Symptoms include sudden wheeziness, difficulty in breathing or dizziness, swelling of the eyelids, face, lips or throat.
If you have an erection which lasts for more than 4 hours, you should contact a doctor immediately. Symptoms may include severe peeling and swelling of the skin, blistering of the mouth, genitals and around the eyes, fever. Very common may affect more than 1 in 10 people: Common may affect up to 1 in 10 people: Nausea,, facial flushing, hot flush symptoms include a sudden feeling of heat in your upper body , indigestion, colour tinge to vision, blurred vision ,visual disturbance,,stuffy nose and dizziness.
Uncommon may affect up to 1 in people: Rare may affect up to 1 in 1, people: Fainting, stroke, heart attack, irregular heartbeat, temporary decreased blood flow to parts of the brain, feeling of tightening of the throat, numb mouth, bleeding at the back of the eye, double vision, reduced sharpness of vision, abnormal sensation in the eye, swelling of the eye or eyelid, small particles or spots in your vision, seeing halos around lights, dilation of the pupil of the eye, discolouration of the white of the eye, penile bleeding, presence of blood in semen, dry nose, swelling of the inside of the nose, feeling irritable and sudden decrease or loss of hearing.
From post-marketing experience cases of: Of note, most, but not all, of the men who experienced these side effects had heart problems before taking this medicine. It is not possible to determine whether these events were directly related to Sildenafil.
Reporting of side effects If you get any side effects, talk to your doctor or pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at www. How to store Sildenafil Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton and on the blister after EXP. The expiry date refers to the last day of that month.
Store in the original container in order to protect from light. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment. Contents of the pack and other information What Sildenafil contains - The active substance is sildenafil. Both sildenafil and the active metabolite have terminal half-lives of about 4 hours.
Population Pharmacokinetics Age, gender, race, and renal and hepatic function were included as factors assessed in the population pharmacokinetic model to evaluate sildenafil pharmacokinetics in patients with PAH. The dataset available for the population pharmacokinetic evaluation contained a wide range of demographic data and laboratory parameters associated with hepatic and renal function.
None of these factors had a significant impact on sildenafil pharmacokinetics in patients with PAH. There was also a doubling of Cmin levels compared to healthy volunteers. Patients with severe hepatic impairment Child-Pugh class C have not been studied. Therefore, inhibitors of these isoenzymes may reduce sildenafil clearance and inducers of these isoenzymes may increase sildenafil clearance.
Sildenafil is not expected to affect the pharmacokinetics of compounds which are substrates of these CYP enzymes at clinically relevant concentrations.
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