For sinusitis Adult dosage ages 18 years and older Typical dosage is to take mg once per day for three days. Child dosage ages 0 to 6 months This drug should not be used in children who are younger than 6 months. For skin and skin structure infections Adult dosage ages 18 years and older Your doctor may prescribe mg taken in a single dose on day 1, followed by mg once per day on days 2 through 5.
For genital ulcer disease Adult dosage ages 18 years and older The doctor will typically prescribe a single 1-gram dose. For community-acquired pneumonia Adult dosage ages 18 years and older Your doctor may prescribe mg in a single dose on day 1, followed by mg once per day on days 2 through 5.
For mycobacterium avium complex disease Adult dosage ages 18 years and older For treatment, typical dosage is mg once per day, taken with the drug ethambutol. For prevention, typical dosage is 1, mg once per week. For pharyngitis or tonsillitis Adult dosage ages 18 years and older Your doctor may prescribe mg in a single dose on day 1, followed by mg once per day on days 2 through 5.
Child dosage ages 0 to 2 years This drug should not be used for this condition in children who are younger than 2 years. Our goal is to provide you with the most relevant and current information. It is a macrolide-type antibiotic. It works by stopping the growth of bacteria. This medication will not work for viral infections such as common cold , flu. Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness. Read the Patient Information Leaflet if available from your pharmacist before you start taking azithromycin and each time you get a refill.
If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually once daily with or without food. You may take this medication with food if stomach upset occurs. The dosage is based on your medical condition and response to treatment. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at the same time each day. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days.
Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection. Antacids containing aluminum or magnesium may decrease the absorption of azithromycin if taken at the same time. If you take an antacid that contains aluminum or magnesium, wait at least 2 hours before or after taking azithromycin.
Tell your doctor if your condition persists or worsens. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Carbamazepine In a pharmacokinetic interaction study in healthy volunteers, no significant effect was observed on the plasma levels of carbamazepine or its active metabolite in patients receiving concomitant azithromycin. Because macrolides inhibit this enzyme, concomitant administration of cisapride may cause the increase of QT interval prolongation, ventricular arrhythmias and torsades de pointes.
Cimetidine In a pharmacokinetic study investigating the effects of a single dose of cimetidine, given 2 hours before azithromycin, on the pharmacokinetics of azithromycin, no alteration of azithromycin pharmacokinetics was seen. Coumarin-Type Oral Anticoagulants In a pharmacokinetic interaction study, azithromycin did not alter the anticoagulant effect of a single 15 mg dose of warfarin administered to healthy volunteers.
There have been reports received in the post-marketing period of potentiated anticoagulation subsequent to coadministration of azithromycin and coumarin-type oral anticoagulants.
Although a causal relationship has not been established, consideration should be given to the frequency of monitoring prothrombin time when azithromycin is used in patients receiving coumarin-type oral anticoagulants. Consequently, caution should be exercised before considering concurrent administration of these drugs.
If coadministration of these drugs is necessary, cyclosporin levels should be monitored and the dose adjusted accordingly. Efavirenz Coadministration of a mg single dose of azithromycin and mg efavirenz daily for 7 days did not result in any clinically significant pharmacokinetic interactions. Fluconazole Coadministration of a single dose of mg azithromycin did not alter the pharmacokinetics of a single dose of mg fluconazole.
Indinavir Coadministration of a single dose of mg azithromycin had no statistically significant effect on the pharmacokinetics of indinavir administered as mg three times daily for 5 days.
Methylprednisolone In a pharmacokinetic interaction study in healthy volunteers, azithromycin had no significant effect on the pharmacokinetics of methylprednisolone. Nelfinavir Coadministration of azithromycin mg and nelfinavir at steady state mg three times daily resulted in increased azithromycin concentrations.
No clinically significant adverse effects were observed and no dose adjustment is required. Rifabutin Coadministration of azithromycin and rifabutin did not affect the serum concentrations of either drug.
Neutropenia was observed in subjects receiving concomitant treatment of azithromycin and rifabutin. Although neutropenia has been associated with the use of rifabutin, a causal relationship to combination with azithromycin has not been established see Section 4.
Sildenafil In normal healthy male volunteers, there was no evidence of an effect of azithromycin mg daily for 3 days on the AUC and Cmax of sildenafil or its major circulating metabolite. Terfenadine Pharmacokinetic studies have reported no evidence of an interaction between azithromycin and terfenadine. There have been rare cases reported where the possibility of such an interaction could not be entirely excluded; however there was no specific evidence that such an interaction had occurred.
Theophylline There is no evidence of a clinically significant pharmacokinetic interaction when azithromycin and theophylline are co-administered to healthy volunteers. Triazolam In 14 healthy volunteers, coadministration of azithromycin mg on Day 1 and mg on Day 2 with 0. Azithromycin serum concentrations were similar to those seen in other studies. Substances that prolong the QT interval Azithromycin should not be used concurrently with other active substances that prolong the QT interval see section 4.
In reproduction toxicity studies in animals azithromycin was shown to pass the placenta, but no teratogenic effects were observed. The safety of azithromycin has not been confirmed with regard to the use of the active substance during pregnancy. Therefore Azithromycin should only be used during pregnancy if the benefit outweighs the risk. Lactation Azithromycin has been reported to be secreted into human breast milk, but there are no adequate and well-controlled clinical studies in nursing women that have characterized the pharmacokinetics of azithromycin excretion into human breast milk.
Fertility In fertility studies conducted in rat, reduced pregnancy rates were noted following administration of azithromycin. The relevance of this finding to humans is unknown.
In the 5mg -Call your doctor for medical advice about side effects. These antacids can make azithromycin less effective when taken azithromycin the same time, azithromycin 5mg. The dose and length of treatment may not be the same for every type of infection. Common azithromycin side effects may include: Efavirenz Coadministration of a mg single dose of azithromycin and mg efavirenz daily 5mg 7 days did not result in any clinically significant pharmacokinetic interactions. This medication will not work for viral infections such as common coldflu. Therefore as the following situations may lead to an increased risk for ventricular arrhythmias including torsade de pointes which can lead to cardiac arrest, azithromycin 5mg, azithromycin should be azithromycin with caution in patients with ongoing proarrhythmic conditions especially women and elderly patients such as patients: Substances that prolong the QT interval Azithromycin should not be used concurrently with other active substances that prolong the QT interval see section 4. Lactation Azithromycin has been reported to be secreted into human breast milk, but there are no adequate and well-controlled clinical studies in nursing women that have characterized the pharmacokinetics of azithromycin excretion into human breast milk, azithromycin 5mg. Stir this mixture and drink all of it right away. Not all possible interactions are listed in this medication guide.
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