Always keep a current list of the drugs and supplements you take and review it with your health care providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products.

This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Tell your health care provider about any negative side effects from prescription drugs. You can also report them to the U. Food and Drug Administration by visiting www. I have been taking pravastatin 40 mg for a couple of years, but I have joint pain everyday.

If the symptoms of muscle pain or weakness are accompanied by tiredness, fever, nausea and vomiting, brown or dark-colored urine or yellowing skin, patients should contact their health care provider. The drug information does not suggest that one statin is more likely to cause muscle pain than another.

My husband has been really sick the past 2 months. He's had nausea, diarrhea, muscle weakness, and fatigue. He has taken pravastatin for almost a year. He takes it at night, wakes up every morning sick to his stomach, cannot eat, and has a loss of appetite. Also had symtoms of a heart attack. He had his heart checked and is okay. Can pravastatin being causing these symptoms? Pravastatin works in the body by blocking the production of some cholesterol. The medication lowers LDL low density lipoprotein and total cholesterol.

The incidence was reported at 7 percent. Diarrhea is a reported side effect in 6 percent of patients. Heartburn has also been reported in 3 percent of patients during clinical trials of the medication. Fatigue was reported in 4 percent of patients and dizziness has an incidence of reporting at 1 percent to 3 percent.

Chest pain is another possible side effect and was reported in 4 percent of patients. Muscle weakness was reported in less than 1 percent of patients. This is not a complete list of all the possible side effects associated with the use of pravastatin. Myopathy or muscle weakness could be a serious side effect of pravastatin. The fear is that it could be related to rhabdomyolysis, which is the breakdown of muscles.

Rhabdomyolysis is a serious medical condition that has been seen with the use of the class of medications that pravastatin belongs to. Medical references recommend that patients taking pravastatin should report to their physician any unexplained muscle pain, weakness, tenderness or brown colored urine.

The recommendation is made to talk to your husband's physician regarding the symptoms that he is experiencing. His physician will be able to determine the best course of action and diagnose his symptoms. Treatment options, which may include a change in medication, will need to be determined by his physician.

He should not stop taking or change the dosage of his medication without first talking to his physician. For more specific information, consult with your husband's doctor or pharmacist for guidance based on his health status and current medications, particularly before taking any action. This list is not complete and other drugs may interact with pravastatin. Tell your doctor about all medications you use.

This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Where can I get more information? Your pharmacist can provide more information about pravastatin. Severe muscle breakdown is an exceedingly rare, but possible, side effect of pravastatin use. About Diabetes Risk A July study published in "Circulation" reported an increased diabetes risk associated with extended statin use, especially when prescribed in high doses.

However, the researchers found no significant increase in diabetes risk with pravastatin use. In fact, pravastatin is the only statin drug that does not carry a warning about a possible risk of high blood sugar levels associated with its use.

Warfarin and other oral anticoagulants: Bioavailability parameters at steady state for pravastatin were not altered following administration with warfarin. Chronic dosing of the two products did not produce any changes in the anticoagulant action of warfarin.

Products metabolised by cytochrome P Pravastatin is not metabolised to a clinically significant extent by the cytochrome P system.

This is why products that are metabolised by, or inhibitors of, the cytochrome P system can be added to a stable regimen of pravastatin without causing significant changes in the plasma levels of pravastatin as have been seen with other statins.

Although these changes were minor, caution should be exercised when associating pravastatin with erythromycin or clarithromycin. In interaction studies, no statistically significant differences in bioavailability were observed when pravastatin was administered with acetylsalicylic acid, antacids when given one hour prior to pravastatin , nicotinic acid or probucol.

Pravastatin is contraindicated during pregnancy and should be administered to women of childbearing potential only when such patients are unlikely to conceive and have been informed of the potential risk. Special caution is recommended in adolescent females of childbearing potential to ensure proper understanding of the potential risk associated with pravastatin therapy during pregnancy.

If a patient plans to become pregnant or becomes pregnant, the doctor has to be informed immediately and pravastatin should be discontinued because of the potential risk to the foetus. A small amount of pravastatin is excreted in human breast milk, therefore pravastatin is contraindicated during breastfeeding see section 4.

However, when driving vehicles or operating machines, it should be taken into account that dizziness and visual disturbances may occur during treatment. Over 19, patients were followed for a median of 4.

If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this medicine. Talk to your doctor or pharmacist before taking Pravastatin: Pravastatin sodium 10 mg, 20 mg and 40 mg tablets Pravastatin sodium 10 mg, 20 mg and 40 mg tablets Package leaflet: Information for the user The name of your medicine is Pravastatin sodium 10 mg , 20mg or 40mg tablets, which will be referred to as Pravastatin throughout this leaflet Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

You may need to read it again. Transient, asymptomatic eosinophilia has been reported. Eosinophil counts usually returned to normal despite continued therapy. Limit Pravastatin to 20 mg once daily for concomitant use with cyclosporine [see Dosage and Administration 2. Limit Pravastatin to 40 mg once daily for concomitant use with clarithromycin [see Dosage and Administration 2. Pravastatin should be used cautiously with macrolide antibiotics due to a potential increased risk of myopathies.

Other Fibrates Because it is known that the risk of myopathy during treatment with HMG-CoA reductase inhibitors is increased with concurrent administration of other fibrates, Pravastatin Sodium should be administered with caution when used concomitantly with other fibrates [see Warnings and Precautions 5. Niacin The risk of skeletal muscle effects may be enhanced when Pravastatin is used in combination with niacin; a reduction in Pravastatin Sodium dosage should be considered in this setting [see Warnings and Precautions 5.

As safety in pregnant women has not been established and there is no apparent benefit to therapy with Pravastatin Sodium during pregnancy, Pravastatin Sodium should be immediately discontinued as soon as pregnancy is recognized [see Contraindications 4.

Limited published data on the use of Pravastatin Sodium in pregnant women are insufficient to determine a drug-associated risk of major congenital malformations or miscarriage.

PRAVASTATIN SODIUM 40 MG TABLETS

Every effort has been made to ensure that the information provided by on this page is accurate, pravastatin 40mg tab int, int, and complete, but no guarantee is made to that effect. An tab in the incidence of myopathy has also been described in patients receiving 40mg statins in combination with inhibitors of cytochrome P pravastatin. Data Human Data Limited published data on Pravastatin have not shown an increased risk of major congenital malformations or miscarriage. Is it possible to have lower back spasms as a side effect of pravastatin? The proposed dose is 40 mg. Other Fibrates Because it is known that the risk of myopathy during treatment with HMG-CoA pravastatin inhibitors is increased with concurrent administration of other fibrates, Pravastatin Sodium should be administered with caution when used concomitantly with other fibrates [see Warnings and Precautions 5, pravastatin 40mg tab int. Products metabolised by cytochrome P Tab your cholesterol can help prevent heart attack, stroke, pravastatin 40mg tab int, and vascular diseases. About Diabetes Risk A July study published 40mg "Circulation" reported an increased diabetes risk associated int extended statin use, especially when prescribed in high doses.

Pravastatin 40 mg Tablets Mislabeling Recall – Tablets Contain Bupropion

Pravastatin is metabolized by the liver and if there is damage done to the liver by the alcohol, the pravastatin may cause more damage and be harmful. Sarah Lewis, PharmD Q: Remember to always consult your physician or health care provider before starting, stopping, or altering a treatment or health care regimen. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: It is very important to continue to follow your doctor's advice about diet and exercise. Pravastatin Tablets 40 mg: Taking Pravastatin with fusidic acid may rarely lead to muscle weakness, tenderness or pain rhabdomyolysis. Despite this decrease in systemic bioavailability, the efficacy of Pravastatin administered once daily in the evening, although not statistically significant, was marginally more effective than that after a morning dose, pravastatin 40mg tab int. Pravastatin is a medication that is used in the treatment of high cholesterol.

What Is The Drug Pravastatin?

Generic Alternative to Pravachol 40mg

Muscle Effects Because some statins may cause muscle aches tab even severe muscle breakdown, the PPP project specifically examined pravastatin and muscle 40mg effects, pravastatin 40mg tab int. He should not stop taking or change the dosage of his medication without first talking to his physician. In some patients, however, the increase in pravastatin exposure may be larger, pravastatin 40mg tab int. Pravachol works by reducing the production pravastatin cholesterol by the liver. Pravastatin Sodium 40mg passes into breast milk and may have undesirable effects on a nursing infant, pravastatin 40mg tab int. There is no dose adjustment necessary in these patients unless there are predisposing risk factors see section 4. Do not double the dose to catch up. Do not start or stop int medications or treatments without first pravastatin to your tab. Patients at risk fasting glucose 5. It belongs to a group of drugs known as "statins. You can also int them to the U. Taking pravastatin and red yeast rice products together can increase your 40mg of serious muscle and liver problems. Lactation Risk Summary Pravastatin use is contraindicated during breastfeeding [see Contraindications 4.

The Great Cholesterol Deception--The Story Behind the Statins

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