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Valium Description Valium 10 mg from Roche Roche Valium Diazepam is an antianxiety agent benzodiazepineused primarily for short-term relief of from to moderate anxiety. It may also be used to treat symptoms of acute alcohol withdrawals, to help control epilepsy, or to relieve muscle spasms, valium from online pharmacy. Diazepam is a long-acting oral and parenteral benzodiazepine.
Diazepam is pharmacy to chlordiazepoxide and clorazepate in that all three online the same active metabolite. Diazepam is used orally for the short-term management of anxiety disorders and acute alcohol withdrawal, and as a skeletal muscle relaxant.
Parenterally, it is indicated as an antianxiety agent, valium from online pharmacy, sedative, amnestic, anticonvulsant, skeletal muscle relaxant, anesthetic adjunct, valium as a treatment for alcohol withdrawal. In addition to treating status epilepticus, percocet 15mg 187 has recently been shown effective in preventing recurrence of febrile seizures.
I Although diazepam has been the benzodiazepine of choice for status epilepticus, recent evidence indicates that lorazepam may be more beneficial because it provides longer control of seizures and produces less cardiorespiratory depression.
Diazepam was approved by the FDA in November Phase III data for a rectal formulation of diazepam in the treatment of acute repetitive seizures was completed April The NDA for the rectal formulation Diastat is expected to be filed in Diazepam is a schedule IV controlled substance. Benzodiazepines act at the level of the limbic, thalamic, and hypothalamic regions of the CNS, and can produce any level of CNS depression required including sedation, hypnosis, skeletal muscle relaxation, anticonvulsant activity, and coma.
The action of these drugs is mediated through the inhibitory neurotransmitter gamma-aminobutyric online GABA. Central benzodiazepine receptors interact allosterically with GABA receptors, potentiating the effects of GABA and increasing the inhibition of the ascending reticular activating system. Evidence suggests that GABA pharmacies are heterogeneous from many different subtypes, which may account for the various effects of GABA receptor agonists and benzodiazepines.
Midazolam, valium from online pharmacy, for example, has twice the affinity for benzodiazepine receptors than diazepam. The antianxiety action of benzodiazepines may be a result of their ability to block cortical and limbic arousal following stimulation of the reticular pathways while muscle relaxation properties are mediated by inhibiting both mono-and polysynaptic pharmacies.
Benzodiazepine can also depress muscle and motor nerve function directly, valium from online pharmacy. Animal online of the anticonvulsant actions suggest that benzodiazepines augment presynaptic inhibition of neurons, thereby limiting the spread from electrical activity, although they do not actually inhibit the abnormally valium focus.
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A viscous online intended for rectal administration in undergoing investigation. Diazepam is the most rapidly absorbed benzodiazepine following an oral dose; however, absorption following an IM injection is slow and erratic.
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The onset of action after an IV dose is minutes. The duration for some clinical effects e. Diazepam is widely distributed, with CSF levels similar to plasma levels. This benzodiazepine crosses the placenta and distributes into breast milk see Contraindications. The disparity from pharmacy half-life and duration of action for some conditiona may be partially explained by pharmacy shifts in distribution of diazepam out of the CNS.
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