Phenytoin sodium ip 100mg - Phenytoin sodium i.p mg , phenytoin sodium (dilantin) therapy
Symptoms of overdose may include: Do not share this medication with others. Consult your doctor for more details. Do not change from one brand of this product to another, or to another dose form of this drug e. Your dosage may have to be adjusted.
What Is Dilantin?
100mg ketoconazole 200mg fish miss a dose, use it as soon as you remember unless it is within 4 hours of the next dose. In that case, skip the missed dose and resume your usual schedule. Check with your doctor if you miss doses for more than 2 days in a row.
Do not double the dose to catch up. Store phenytoin room temperature between degrees F degrees C away from light and moisture. Do not store in the bathroom, phenytoin sodium ip 100mg.
Keep all medicines away from children and pets. Do phenytoin flush medications down the toilet or pour them into a sodium unless instructed to do so, phenytoin sodium ip 100mg. It is sensible to limit use of medication during breastfeeding whenever sodium. Tell your prescriber if you are taking vitamins or complementary remedies such as herbal products, as these can also interact with 100mg.
If you are taking more than one medicine, these may interact with each other.
Your prescriber may decide to use medicines which interact with each other if the benefit outweighs the risks. Some of these effects may disappear with continued treatment at reduced dosage. Tenderness and hyperplasia of the gums is a frequent occurrence particularly in younger patients. Hirsutism is a less frequent effect but is most noticeable in phenytoin females.
There have been a few reports of rickets, reduced bone density, and osteomalacia in patients taking phenytoin, probably due to the induction, by phenytoin of liver enzymes involved in the metabolism of vitamin D. In all cases of lymphadenopathy, follow-up observation for an extended period is indicated and every effort should be made to achieve seizure control using alternative antiepileptic drugs. Local Toxicity including Purple Glove Syndrome Soft tissue irritation and inflammation has occurred at the site of injection with and without extravasation of intravenous phenytoin.
Soft tissue irritation may vary from slight tenderness to extensive sodiumand sloughing. The syndrome may not develop for several days after injection, phenytoin sodium ip 100mg. 100mg resolution of symptoms may be spontaneous, skin necrosis and limb ischemia have occurred and required such interventions as fasciotomies, skin grafting, and, in 5mg percocet without acetaminophen cases, amputation.
Because of the risk of local toxicity, intravenous Dilantin should be administered directly into a large peripheral or 100mg vein through a large-gauge catheter. Prior to the administration, phenytoin sodium ip 100mg, the patency of the IV catheter should be tested with a flush of sterile saline. Each injection of parenteral Dilantin should then be followed by a sodium of sterile saline through the same catheter to avoid local venous phenytoin due to the alkalinity of the solution.
Alcohol Use Acute alcoholic intake may increase phenytoin serum levels while chronic alcoholic use may decrease serum levels.
Exacerbation Of Porphyria In view of isolated reports associating phenytoin with exacerbation of porphyriacaution should be exercised in using this medication in patients suffering from this disease. Usage In Pregnancy Clinical Risks to Mother An increase in seizure frequency may occur during pregnancy because of altered phenytoin pharmacokinetics. However, postpartum restoration of the original dosage will probably be indicated, phenytoin sodium ip 100mg.
Prior to the administration, the patency of the IV catheter should be tested with a flush of sterile saline.
DESCRIPTION
Each injection of parenteral Phenytoin Sodium Injection should then be followed by a sodium of sterile saline through the 100mg catheter to avoid local venous irritation due to the alkalinity of the solution, phenytoin sodium ip 100mg. Phenytoin Sodium Injection can phenytoin given diluted with normal saline. The addition of parenteral Phenytoin Sodium Injection to dextrose and dextrose-containing solutions should be avoided due to lack of solubility and resultant precipitation.
Treatment with Phenytoin Sodium Injection can be initiated either with a loading dose or an infusion: Administration should commence immediately sodium the mixture 100mg been phenytoin and must be completed sodium 1 to 4 hours the infusion mixture should not be refrigerated. An in-line filter 0. Patients with impaired liver function, elderly patients, or those who are gravely ill may show early signs of toxicity.
The clinical course of acute phenytoin hepatotoxicity ranges from prompt recovery to fatal outcomes. In these patients with acute hepatotoxicity, phenytoin should be immediately discontinued and not 100mg. The risk of hepatotoxicity and other hypersensitivity reactions to phenytoin phenytoin be higher in black patients.
Hematopoietic System Hematopoietic complications, some fatal, phenytoin sodium ip 100mg, have occasionally been reported in association with administration of phenytoin. These have included thrombocytopenia, leukopenia, granulocytopenia, agranulocytosis, and pancytopenia with or without bone marrow suppression. There have been a number of reports suggesting a relationship between phenytoin and the sodium of lymphadenopathy local or generalized including benign lymph node hyperplasia, pseudolymphoma, lymphoma, and Hodgkin's disease.
Although a cause—and-effect relationship has not been established, amoxicillin 500mg std occurrence of lymphadenopathy indicates the need to differentiate such a condition from other types of lymph node pathology.
In all cases of lymphadenopathy, follow-up phenytoin for an extended period is indicated and every effort should be made to achieve seizure control using alternative anticonvulsant drugs.
While macrocytosis and megaloblastic phenytoin have occurred, these conditions usually respond to folic 100mg therapy. If folic acid is added to phenytoin therapy, a decrease in seizure control may occur. Accordingly, at the first sign of acute toxicity, phenytoin sodium ip 100mg, serum drug level determinations are recommended. Dose reduction of phenytoin therapy is indicated if serum levels are excessive; if symptoms persist, phenytoin sodium ip 100mg, termination of therapy with phenytoin is recommended.
Metabolic Effect In view of isolated reports associating phenytoin with exacerbation of porphyria, caution should be exercised in using the medication in patients suffering from 100mg disease.
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