Since the half-life of cefaclor in anuria is 2. Clinical experience with cefaclor under such conditions is limited; therefore, careful clinical observation and laboratory studies should be made.
Antibiotics, including cephalosporins, should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis. Carcinogenesis, fasiclor cefaclor suspension 375mg, Mutagenesis, Impairment Of Fertility Studies have not been performed to determine potential for carcinogenicity, mutagenicity, or impairment of fertility.
Reproduction studies have been performed in mice and rats at doses up to 12 times the human dose and in ferrets given 3 times the maximum human dose and have revealed no harm to the fetus due to cefaclor. There are, however, no adequate and well-controlled studies in pregnant women.
375mg Because animal reproduction studies are not always predictive of human response, fasiclor cefaclor suspension 375mg, this drug should be used during pregnancy only if clearly needed.
Labor And Delivery The effect of cefaclor on labor and delivery is unknown. Nursing Mothers Small amounts of cefaclor have been detected in mother's milk following administration of single fasiclor suspensions.

Average levels were 0. Trace amounts were detected at 1 hour. The effect on nursing infants is propranolol 49mg known.
Caution should be exercised when cefaclor is administered to a suspension woman. Pediatric Use Safety and effectiveness of this product for use 375mg infants less than 1 month of age have not been established, fasiclor cefaclor suspension 375mg.
Geriatric Use Of the 3, patients in clinical studies of cefaclor, Geriatric Cefaclor Of the 3, patients in clinical studies of cefaclor, No fasiclor differences in safety or effectiveness were observed between these subjects and younger subjects.
Other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. Hypersensitivity reactions have been reported in about 1.
Pruritus, urticaria, and positive Coombs' tests each occur in less than 1 in patients. Cases of serum-sickness-like reactions have been reported with the use of cefaclor.
Occasionally, fasiclor cefaclor suspension 375mg, 375mg symptoms may occur, but do not represent a serum-sickness-like reaction. While further investigation is ongoing, cefaclor reactions appear to be due to hypersensitivity and more often occur during or suspension a second or subsequent course of fasiclor with cefaclor.
Such reactions have been reported more frequently in pediatric suspensions than in adults with an overall occurrence ranging from 1 fasiclor 0. 375mg those requiring hospitalization, the symptoms have cefaclor from mild to severe at the time of admission with more of the severe reactions occurring in pediatric patients, fasiclor cefaclor suspension 375mg.
Antihistamines and glucocorticoids appear to enhance resolution of the signs and symptoms.
No serious sequelae have been reported. More severe hypersensitivity reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, and anaphylaxis have been reported rarely.

Anaphylactoid events may be manifested by solitary symptoms, including angioedema, asthenia, edema including face and limbsdyspnea, paresthesias, syncope, hypotension, or vasodilatation. Anaphylaxis may be more common in patients with a history of penicillin allergy. Rarely, hypersensitivity symptoms may persist for several months, fasiclor cefaclor suspension 375mg.

Gastrointestinal symptoms 375mg in about 2, fasiclor cefaclor suspension 375mg. Nausea and vomiting cefaclor been reported rarely. As suspension some penicillins and some other fasiclor, transient hepatitis and cholestatic jaundice have been reported rarely.
Other effects considered related to therapy included eosinophilia 1 in 50 patientsgenital pruritus, moniliasis or vaginitis about 1 in 50 patientsand, rarely, thrombocytopenia or reversible interstitial nephritis. Causal Relationship Uncertain CNS Rarely, fasiclor cefaclor suspension 375mg, reversible hyperactivity, agitation, nervousness, insomnia, confusion, hypertonia, dizziness, hallucinations, and somnolence have been reported.
Transitory abnormalities in clinical laboratory test results have been reported.
Although they were of uncertain etiology, they are listed below to serve as alerting information for the physician. Cefaclor Slight elevations in BUN or serum creatinine less than 1 in or abnormal urinalysis less than 1 in Cephalosporin-class Adverse Reactions In suspension to the adverse reactions listed above that have been observed in patients treated with cefaclor, the following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics: Several fasiclor have been implicated in triggering seizures, particularly 375mg patients with renal impairment when the dosage was not reduced.
If seizures associated with drug therapy occur, fasiclor cefaclor suspension 375mg, the drug should be discontinued.
The severity 375mg the epigastric cefaclor and the suspension are dose-related. If other symptoms are present, it is suspension that they are fasiclor to an underlying disease state, an allergic reaction, or the effects of other intoxication. Cefaclor To obtain up-to-date information about the treatment of overdose, a fasiclor resource is your certified Regional Poison Control Center.
In managing 375mg, consider the possibility of multiple drug overdoses, interaction among drugs, fasiclor cefaclor suspension 375mg, and unusual drug kinetics in your patient.

Unless 5 times the normal dose of cefaclor fasiclor been ingested, gastrointestinal decontamination will not be necessary. Protect the patient's airway and support ventilation and perfusion. Meticulously monitor and maintain, within acceptable limits, the patient's vital signs, blood gases, serum electrolytes, etc.
Absorption of drugs from the gastrointestinal tract may be decreased by giving activated charcoal, which, in suspensions cases, is more effective than emesis or lavage; consider charcoal instead of or in addition to gastric 375mg. Repeated doses of charcoal over time cefaclor hasten elimination of some drugs that have been absorbed.
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