Your medicine may need to be changed to treat this. Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea pseudomembranous colitis may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
Hormonal birth control eg, birth control pills may not work as well while you are using Trimox. To prevent pregnancy, use an extra form of birth control eg, condoms. Brown, yellow, or gray tooth discoloration has occurred rarely in some patients taking Trimox.
It occurred most often in children. The discoloration was reduced or removed by brushing or dental cleaning in most cases. Contact your doctor if you experience this effect. Diabetes patients - Trimox may cause the results of some tests for urine glucose to be wrong.
Ask your doctor before you change your diet or the dose of your diabetes medicine. Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed if you use Trimox for a long period of time. These tests may be used to monitor your condition or check for side effects.
Be sure to keep all doctor and lab appointments. Use Trimox with caution in the elderly; they may be more sensitive to its effects, especially patients with kidney problems. Use Trimox with extreme caution in children younger 10 years who have diarrhea or an infection of the stomach or bowel. Caution is advised when using Trimox in children younger 3 months; they may be more sensitive to its effects.
If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Trimox while you are pregnant. Trimox is found in breast milk. If you are or will be breast-feeding while you use Trimox, check with your doctor. Discuss any possible risks to your baby. Monitor therapy BCG Intravesical: Antibiotics may diminish the therapeutic effect of BCG Intravesical.
May decrease the serum concentration of Ampicillin. Chloroquine prescribing information recommends separating administration of ampicillin and chloroquine by at least 2 hours to minimize any potential negative impact of chloroquine on ampicillin bioavailability. Consider therapy modification Cholera Vaccine: Antibiotics may diminish the therapeutic effect of Cholera Vaccine.
Avoid combination Lactobacillus and Estriol: Antibiotics may diminish the therapeutic effect of Lactobacillus and Estriol. Administer oral ampicillin at least two hours before or after lanthanum. Consider therapy modification Methotrexate: Penicillins may increase the serum concentration of Methotrexate. Penicillins may decrease serum concentrations of the active metabolite s of Mycophenolate.
This effect appears to be the result of impaired enterohepatic recirculation. Avoid the routine use of penicillins and probenecid, but this combination may be used advantageously in select cases with careful monitoring. Monitor for toxic effects of penicillins if probenecid is initiated or the dose is increased.
Consider therapy modification Sodium Picosulfate: Antibiotics may diminish the therapeutic effect of Sodium Picosulfate. Consider using an alternative product for bowel cleansing prior to a colonoscopy in patients who have recently used or are concurrently using an antibiotic. Consider therapy modification Tetracyclines: May diminish the therapeutic effect of Penicillins. Consider therapy modification Typhoid Vaccine: Antibiotics may diminish the therapeutic effect of Typhoid Vaccine. Only the live attenuated Ty21a strain is affected.
Vaccination with live attenuated typhoid vaccine Ty21a should be avoided in patients being treated with systemic antibacterial agents. Use of this vaccine should be postponed until at least 3 days after cessation of antibacterial agents.
Consider therapy modification Vitamin K Antagonists eg, warfarin: Penicillins may enhance the anticoagulant effect of Vitamin K Antagonists. Adverse Reactions Central nervous system: Brain disease penicillin-induced , glossalgia, seizure, sore mouth Dermatologic: Erythema multiforme, exfoliative dermatitis, skin rash, urticaria Note: Appearance of a rash should be carefully evaluated to differentiate if possible nonallergic ampicillin rash from hypersensitivity reaction. Incidence is higher in patients with viral infection, Salmonella infection, lymphocytic leukemia, or patients that have hyperuricemia.
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