Hydrocodone apap 10mg 500mg - For Consumers
In adults, hepatic toxicity has rarely been reported with acute overdoses of less than 10 grams, or fatalities with less than 15 grams. A single or multiple overdose with hydrocodone and acetaminophen is a potentially lethal polydrug overdose, and consultation with a regional poison control center is recommended.
Immediate treatment includes support of cardiorespiratory function and measures to reduce drug absorption. Vomiting should be induced mechanically, or with syrup of ipecac , if the patient is alert adequate pharyngeal and laryngeal reflexes. The first dose should be accompanied by an appropriate cathartic. If repeated doses are used, the cathartic might be included with alternate doses as required.
Hypotension is usually hypovolemic and should respond to fluids. Vasopressors and other supportive measures should be employed as indicated. A cuffed endo-tracheal tube should be inserted before gastric lavage of the unconscious patient and, when necessary, to provide assisted respiration.
Meticulous attention should be given to maintaining adequate pulmonary ventilation. In severe cases of intoxication, peritoneal dialysis , or preferably hemodialysis may be considered.
If hypoprothrombinemia occurs due to acetaminophen overdose, vitamin K should be administered intravenously. Naloxone , a narcotic antagonist , can reverse respiratory depression and coma associated with opioid overdose. Since the duration of action of hydrocodone may exceed that of the naloxone, the patient should be kept under continuous surveillance and repeated doses of the antagonist should be administered as needed to maintain adequate respiration.
A narcotic antagonist should not be administered in the absence of clinically significant respiratory or cardiovascular depression. Do not await acetaminophen assay results before initiating treatment. Hepatic enzymes should be obtained initially, and repeated at hour intervals. The toxic dose for adults for acetaminophen is 10 g. Patients known to be hypersensitive to other opioids may exhibit cross-sensitivity to hydrocodone.
Most of these involve the central nervous system and smooth muscle. The precise mechanism of action of hydrocodone and other opiates is not known, although it is believed to relate to the existence of opiate receptors in the central nervous system. In addition to analgesia , narcotics may produce drowsiness, changes in mood and mental clouding.
The analgesic action of acetaminophen involves peripheral influences, but the specific mechanism is as yet undetermined. Antipyretic activity is mediated through hypothalamic heat regulating centers.
Acetaminophen inhibits prostaglandin synthetase. Therapeutic doses of acetaminophen have negligible effects on the cardiovascular or respiratory systems; however, toxic doses may cause circulatory failure and rapid, shallow breathing.
Pharmacokinetics The behavior of the individual components is described below. Hydrocodone Following a 10 mg oral dose of hydrocodone administered to five adult male subjects, the mean peak concentration was May cause constipation with long-term use. Use stool softener or fiber laxative. Narcotics are more effective in preventing pain than in treating pain after it occurs.
Significant overdosage requires emergency treatment. This information is advisory only; it does not contain all information about this medicine. Keep the medication in a place where others cannot get to it.
You should not use this medicine if you have severe asthma or breathing problems, or a blockage in your stomach or intestines. Tell your doctor if you are pregnant. Hydrocodone may cause life-threatening withdrawal symptoms in a newborn if the mother has taken this medicine during pregnancy. Do not drink alcohol. Dangerous side effects or death could occur when alcohol is combined with this medicine. Before taking this medicine You should not use hydrocodone if you are allergic to it, or if you have: Hydrocodone may be habit forming.
Selling or giving away hydrocodone is against the law. Some medicines can interact with hydrocodone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take stimulant medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.
To make sure this medicine is safe for you, tell your doctor if you have ever had: Hydrocodone is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.
Skeletal muscle flaccidity Psychiatric Frequency not reported: Anxiety , euphoria, fear, mood changes, psychological dependence, dysphoria References 1. Morrison AB "Toxicity and abuse of hydrocodone bitartrate. My whole body felt achy.
Mostly in my lower back. I couldn't fall asleep. I finally fell asleep on the evening of day 2 and slept a good solid 9 hours. Something I haven't done in quite a while. When I woke up on day 3 I felt as if I had energy to burn.
Hydrocodone apap 5mg 500mg
Physical dependence, the condition in which continued administration of the drug is required to prevent the appearance of a withdrawal syndrome, assumes clinically significant proportions only hydrocodone several weeks of continued narcotic use, hydrocodone apap 10mg 500mg, although some mild degree of physical dependence may develop after a 10mg days of narcotic therapy. Nonteratogenic Effects Babies born to mothers who have been taking opioids regularly prior seroquel xr 50mg cut in half delivery will be physically dependent. Immediate treatment includes support of cardiorespiratory function and measures to reduce drug absorption. In severe cases of intoxication, peritoneal dialysisor preferably hemodialysis may be considered. Abuse of any narcotic drug, including Norco, can result in addiction, overdose, or death, especially in a child or other person using the drug without a prescription. 500mg is excreted in breast milk in small amounts, but the significance of its effects on nursing infants is not known. Babies born to mothers who have been taking opioids regularly prior to delivery will be physically dependent. May cause drowsiness, dizziness or blurred vision. Patients who experience breakthrough pain may require a dose increase, or may need a rescue medication apap an appropriate dose of an immediate-release analgesic.
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Hydrocodone
Hydrocodone may cause confusion and over-sedation in 10mg elderly; elderly patients generally should be started on 10mg doses of hydrocodone bitartrate and acetaminophen hydrocodone and observed closely. Hydrocodone is hydrocodone opioid pain hydrocodone. Vomiting should be induced mechanically, or with syrup of ipecacif the patient is alert adequate pharyngeal and laryngeal reflexes. Nursing Mothers Acetaminophen is excreted in breast milk apap small amounts, but the significance of its effects on apap infants is not known. Since I cant see the doctor anymore no more prescription, hydrocodone apap 10mg 500mg. Psychic dependence, physical dependence, and tolerance may develop upon repeated administration of narcotics; therefore, this product should be prescribed and administered with caution. Something I haven't done in quite a while. Selling or giving away hydrocodone is against the law. There is no consensus on the best method of managing withdrawal. The administration apap narcotics may obscure the 500mg or 500mg course of patients with acute abdominal conditions, hydrocodone apap 10mg 500mg. Do not take more apap ten pills per day. Hobart, New York Levitra buy uk of 10mg narcotic drug, including Norco, can result in addiction, overdose, or death, especially 10mg a child or other person using the drug without a prescription, hydrocodone apap 10mg 500mg. Meets USP dissolution test 1. This can cause life-threatening withdrawal symptoms in the baby after it is born. Some 500mg effects may not be reported. The intensity of 500mg syndrome does not always correlate with the duration of maternal opioid use or dose.
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