Nursing Mothers Ethambutol HCl is excreted into breast milk. The use of Ethambutol HCl should be considered only if the expected benefit to the mother outweighs the potential risk to the infant. Pediatric Use Ethambutol HCl Ethambutol hydrochloride is not recommended for use in pediatric patients under thirteen years of age since safe conditions for use have not been established.
One study of patients, 65 years and older, on multiple drug antituberculosis regimens included 94 patients on Ethambutol HCl. No differences in safety or tolerability were observed in these patients compared with that reported in adults in general. Other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.
Adverse Reactions Ethambutol HCl may produce decreases in visual acuity, including irreversible blindness, which appear to be due to optic neuritis. Optic neuropathy including optic neuritis or retrobulbar neuritis occurring in association with Ethambutol therapy may be characterized by one or more of the following events: These events have also been reported in the absence of a diagnosis of optic or retrobulbar neuritis. Patients should be advised to report promptly to their physician any change of visual acuity.
The change in visual acuity may be unilateral or bilateral and hence each eye must be tested separately and both eyes tested together. Testing of visual acuity should be performed before beginning Ethambutol HCl therapy and periodically during drug administration, except that it should be done monthly when a patient is on a dosage of more than 15 mg per kilogram per day.
Carry on taking them for as long as you have been told unless you have any problems in which case, check with your doctor. For prevention and first time treatment of tuberculosis: The usual dose is 15 mg per kg of body weight each day. Second time or subsequent treatment of tuberculosis: The usual dose is 25 mg per kg of body weight each day for the first 60 days, reducing to 15 mg per kg of body weight each day for as long as necessary.
For prevention of tuberculosis: First time, second time or subsequent treatment of tuberculosis: One of the antibiotics, ethambutol, isn't recommended for patients who have cataracts, and I was recently diagnosed with moderate cataracts. I worry that my primary care doctor, pulmonologist, and infectious disease doctors don't communicate with each other, and I'm stalling on taking these drugs.
What should I do? Talk to your doctor or pharmacist about the medications you take. When your doctor prescribes a new medication, discuss all over-the-counter medications and prescriptions, dietary supplements, vitamins, botanicals, minerals, and herbals you take, as well as the foods you eat. Always keep a current list and review it with your health care providers and your pharmacist. Ethambutol may produce vision problems, which could be related to the dose and duration of the treatment.
This effect is generally reversible when the drug is stopped, but irreversible blindness has been reported. For more specific information, consult with your doctor or pharmacist for guidance based on your specific condition and current medications.
Before taking this medication, tell your doctor if you have ever had an allergic reaction to ethambutol; cataracts , diabetic retinopathy, or optic neuritis; or kidney disease. You may not be able to take ethambutol, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. It is not known whether ethambutol will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
It is also not known whether ethambutol will be harmful to a nursing baby. Do not take this medication without first talking to your doctor if you are breast -feeding a baby. How should I take ethambutol Myambutol? Take ethambutol exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. This effect may be related to dose and duration of treatment.
This effect is generally reversible when administration of the drug is discontinued promptly. However, irreversible blindness has been reported. Baseline and periodic assessment of hepatic function should be performed. Patients with decreased renal function need the dosage reduced as determined by serum levels of MYAMBUTOL, since the main path of excretion of this drug is by the kidneys.
Because this drug may have adverse effects on vision, physical examination should include ophthalmoscopy , finger perimetry and testing of color discrimination. In patients with visual defects such as cataracts, recurrent inflammatory conditions of the eye, optic neuritis, and diabetic retinopathy , the evaluation of changes in visual acuity is more difficult, and care should be taken to be sure the variations in vision are not due to the underlying disease conditions.
In such patients, consideration should be given to relationship between benefits expected and possible visual deterioration since evaluation of visual changes is difficult.
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